Symbol
Name
ID

Lmx1b
LIM homeobox transcription factor 1 beta
MGI:1100513

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes

Abnormal digit morphology

Clinodactyly of the 5th finger

Absent distal interphalangeal creases

Contracture of the distal interphalangeal joint of the fingers

Proximal finger joint hyperextensibility

Abnormal femur morphology

Disproportionate prominence of the femoral medial condyle

Abnormal tibia morphology

Patellar aplasia

Patellar hypoplasia

Dislocated radial head

Hypoplastic radial head

Elongated radius

Achilles tendon contracture

Equinovarus deformity

Pes planus

Talipes calcaneovalgus

Talipes calcaneovarus

Talipes equinovalgus

Talipes equinovarus

Abnormality of the knee

Abnormal patella morphology

Patellar dislocation

Knee flexion contracture

Knee joint hypermobility

Quadriceps aplasia

Biceps aplasia

Triceps aplasia

Abnormality of the elbow

Cubitus valgus

Elbow flexion contracture

Limited elbow extension

Limited pronation/supination of forearm

Disease(s) Associated with LMX1B

nail-patella syndrome

Mouse Phenotypes		abnormal foot pad morphology	absent ulna	abnormal ankle joint morphology	absent patella	abnormal metacarpal bone morphology	abnormal limb development	abnormal limb position
Availability	Mouse Genotype	abnormal foot pad morphology	absent ulna	abnormal ankle joint morphology	absent patella	abnormal metacarpal bone morphology	abnormal limb development	abnormal limb position
	Lmx1b^Icst/Lmx1b^Icst
	Lmx1b^tm1Rjo/Lmx1b^tm1Rjo
	Lmx1b^{tm3(cre/ERT2)Rjo}/Lmx1b^{tm3(cre/ERT2)Rjo}
	Gt(ROSA)26Sor^{tm1(CAG-Lmx1b,ALPP)Rjo}/Gt(ROSA)26Sor⁺ Sox9^tm3(cre)Crm/Sox9⁺ (conditional)
	Gt(ROSA)26Sor^{tm1(CAG-Lmx1b,ALPP)Rjo}/Gt(ROSA)26Sor⁺ Tg(Prrx1-cre)1Cjt/0 (conditional)
	Lmx1b^tm1Rjo/Lmx1b^tm1Zfc Sox9^tm3(cre)Crm/Sox9⁺ (conditional)
	Lmx1b^tm1Rjo/Lmx1b^tm1Zfc Tg(Prrx1-cre)1Cjt/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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