|
Symbol Name ID |
Pitx3
paired-like homeodomain transcription factor 3 MGI:1100498 |
| Darker colors indicate more annotations |
| Human Phenotypes | Opacification of the corneal stroma |
Microcornea |
Cataract |
Developmental cataract |
Posterior polar cataract |
Progressive cataract |
Nuclear cataract |
Iris coloboma |
Ocular anterior segment dysgenesis |
Peters anomaly |
Microphthalmia |
Ocular hypertension |
Strabismus |
Nystagmus |
Visual impairment |
Amblyopia |
Blindness |
Glaucoma |
| Disease(s) Associated with PITX3 | ||||||||||||||||||
| anterior segment dysgenesis 1 | ||||||||||||||||||
| cataract | ||||||||||||||||||
| cataract 9 multiple types | ||||||||||||||||||
| cataract 11 multiple types |
| Mouse Phenotypes | enlarged lacrimal gland |
abnormal iris pigmentation |
abnormal eye morphology |
abnormal anterior eye segment morphology |
acoria |
increased cornea thickness |
fused cornea and lens |
abnormal lens development |
aphakia |
abnormal eye distance/ position |
microphthalmia |
eyelids fail to open |
abnormal posterior eye segment morphology |
abnormal ocular fundus morphology |
abnormal retina morphology |
disorganized retina layers |
retina fold |
anophthalmia |
|
| Availability | Mouse Genotype | ||||||||||||||||||
| Pitx3ak/Pitx3ak | |||||||||||||||||||
| Pitx3eyl/Pitx3eyl | |||||||||||||||||||
| Pitx3tm1.1(KOMP)Vlcg/Pitx3tm1.1(KOMP)Vlcg | |||||||||||||||||||
| Pitx3tm1.1Jdr/Pitx3tm1.1Jdr | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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