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Symbol
Name
ID

Fgf10
fibroblast growth factor 10
MGI:1099809

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Enamel hypoplasia	Carious teeth	Widely spaced teeth	Xerostomia	Absent eyelashes	Epicanthus	Lacrimal duct aplasia	Lacrimal gland aplasia	Lacrimal gland hypoplasia	Absent lacrimal punctum
Disease(s) Associated with FGF10	Enamel hypoplasia	Carious teeth	Widely spaced teeth	Xerostomia	Absent eyelashes	Epicanthus	Lacrimal duct aplasia	Lacrimal gland aplasia	Lacrimal gland hypoplasia	Absent lacrimal punctum
aplasia of lacrimal and salivary glands
lacrimoauriculodentodigital syndrome 3

Mouse Phenotypes

abnormal tooth morphology

abnormal incisor morphology

short incisors

small molars

reduced enamel thickness

abnormal palatal mesenchymal cell proliferation

abnormal secondary palate development

palatal shelf fusion with tongue or mandible

xerostomia

abnormal palate morphology

decreased palatal length

absent palatal rugae

cleft secondary palate

abnormal tongue morphology

tongue ankylosis

abnormal nasal gland morphology

abnormal lateral nasal gland morphology

small ears

Availability

Mouse Genotype

Fgf10^tm1Ska/Fgf10^tm1Ska

Fgf10^tm1Wss/Fgf10^tm1Wss

Fgf10^tm1Wss/Fgf10⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23