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Symbol
Name
ID

Cast
calpastatin
MGI:1098236

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Abnormality of metabolism/homeostasis	Elevated circulating C-reactive protein concentration	Elevated erythrocyte sedimentation rate	Joint swelling	Fever	Hematuria	Pyuria	Proteinuria
Disease(s) Associated with CAST	Abnormality of metabolism/homeostasis	Elevated circulating C-reactive protein concentration	Elevated erythrocyte sedimentation rate	Joint swelling	Fever	Hematuria	Pyuria	Proteinuria
rheumatoid arthritis
Sjogren's syndrome
systemic lupus erythematosus

Mouse Phenotypes		increased susceptibility to neuronal excitotoxicity	decreased fasting circulating glucose level	increased circulating phosphate level	increased circulating sodium level	increased circulating alanine transaminase level	decreased physiological sensitivity to xenobiotic
Availability	Mouse Genotype	increased susceptibility to neuronal excitotoxicity	decreased fasting circulating glucose level	increased circulating phosphate level	increased circulating sodium level	increased circulating alanine transaminase level	decreased physiological sensitivity to xenobiotic
	Cast^{tm1.1(KOMP)Vlcg}/Cast^{tm1.1(KOMP)Vlcg}
	Cast^tm1Tcs/Cast^tm1Tcs
	Tg(Myh6-Cast)1Gwd/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23