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Symbol
Name
ID

Dll3
delta like canonical Notch ligand 3
MGI:1096877

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Short neck	Vertebral fusion	Block vertebrae	Rib fusion	Kyphoscoliosis	Abnormal odontoid process morphology	Hemivertebrae	Vertebral segmentation defect	Back pain	Disproportionate short-trunk short stature
Disease(s) Associated with DLL3
spondylocostal dysostosis 1

Mouse Phenotypes

skeleton phenotype

abnormal cranium morphology

abnormal caudal vertebrae morphology

decreased caudal vertebrae number

abnormal skeleton morphology

sternebra fusion

abnormal axial skeleton morphology

abnormal rib morphology

decreased rib number

rib bifurcation

rib fusion

splayed ribs

abnormal thoracic vertebrae morphology

kyphosis

lordosis

abnormal vertebrae morphology

abnormal cervical vertebrae morphology

abnormal lumbar vertebrae morphology

abnormal vertebrae development

abnormal vertebrae number

decreased vertebrae number

vertebral compression

abnormal vertebral arch morphology

vertebral fusion

short vertebral column

decreased compact bone thickness

abnormal trabecular bone morphology

abnormal sclerotome morphology

abnormal bone ossification

Availability

Mouse Genotype

Dll3^oma/Dll3^oma

Dll3^pu-J/Dll3^pu-J

Dll3^pu/Dll3^pu

Dll3^tm1Rbe/Dll3^tm1Rbe

Dll3^tm1Rbe/Dll3⁺

*

Tg(Dll1-Dll3)3Gos/?

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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