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Symbol
Name
ID

Cxcr4
C-X-C motif chemokine receptor 4
MGI:109563

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Splenomegaly	Hepatomegaly	Weight loss
Disease(s) Associated with CXCR4	Splenomegaly	Hepatomegaly	Weight loss
lymphoplasmacytic lymphoma
osteosarcoma

Mouse Phenotypes		increased heart weight	cardiac hypertrophy	embryonic growth retardation	growth/size/body region phenotype	polycystic kidney	increased susceptibility to diet-induced obesity	decreased body size	decreased fetal size	enlarged kidney	enlarged spleen
Availability	Mouse Genotype	increased heart weight	cardiac hypertrophy	embryonic growth retardation	growth/size/body region phenotype	polycystic kidney	increased susceptibility to diet-induced obesity	decreased body size	decreased fetal size	enlarged kidney	enlarged spleen
	Cxcr4^b2b220Clo/Cxcr4^b2b220Clo
	Cxcr4^em1(IMPC)Mbp/Cxcr4^em1(IMPC)Mbp
	Cxcr4^tm1Qma/Cxcr4^tm1Qma
	Cxcr4^tm1Yzo/Cxcr4^tm1Yzo
	Cxcr4^em1(IMPC)Mbp/Cxcr4⁺
	Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)				*
	Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Tg(Fabp4-cre)1Rev/0 (conditional)				*
	Cxcr4^tm2Yzo/Cxcr4^tm2Yzo Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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