Symbol
Name
ID

Slc4a2
solute carrier family 4 (anion exchanger), member 2
MGI:109351

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Craniosynostosis	Macrocephaly	Bowing of the long bones	Abnormal metaphysis morphology	Bone pain	Recurrent fractures	Abnormal epiphysis morphology	Abnormal rib morphology	Narrow chest	Osteopetrosis	Reduced bone mineral density
Disease(s) Associated with SLC4A2
osteopetrosis

Mouse Phenotypes

failure of tooth eruption

abnormal osteoclast morphology

abnormal osteoclast physiology

abnormal long bone morphology

abnormal long bone metaphysis morphology

abnormal bone marrow cavity morphology

increased trabecular bone volume

abnormal trabecular bone morphology

increased bone trabecula number

increased trabecular bone thickness

increased bone mass

osteopetrosis

abnormal skeleton development

Availability

Mouse Genotype

Slc4a2^tm1Ges/Slc4a2^tm1Ges

Slc4a2^tm2Ges/Slc4a2^tm2Ges
Ctsk^tm1(cre)Ska/Ctsk⁺ (conditional)

Slc4a2^tm2Ges/Slc4a2^tm2Ges
Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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