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Symbol
Name
ID

Irs2
insulin receptor substrate 2
MGI:109334

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased waist to hip ratio
Disease(s) Associated with IRS2	Increased waist to hip ratio
type 2 diabetes mellitus

Mouse Phenotypes		growth/size/body region phenotype	decreased birth body size	decreased body weight	weight loss	increased body weight	obese	increased body length
Availability	Mouse Genotype	growth/size/body region phenotype	decreased birth body size	decreased body weight	weight loss	increased body weight	obese	increased body length
	Irs2^tm1Mfw/Irs2^tm1Mfw
	Irs2^tm1Tka/Irs2^tm1Tka	*
	Irs2^tm1With/Irs2^tm1With Tg(Ins2-cre)25Mgn/0 (conditional)
	Irs2^tm1With/Irs2^tm1With Tg(Nes-cre)1Kln/0 (conditional)
	Irs2^tm2Mfw/Irs2^tm2Mfw Tg(Ins2-cre)25Mgn/0 (conditional)
	Irs2^tm2Mfw/Irs2^tm2Mfw Tg(Ins2-cre)25Mgn/0 Tg(Ins2-Irs2)13Mfw/0 (conditional)
	Irs2^tm2Tka/Irs2^tm2Tka Tg(Ins2-cre)25Mgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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