|
Symbol Name ID |
Smo
smoothened, frizzled class receptor MGI:108075 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatosplenomegaly |
Peritoneal abscess |
Weight loss |
| Disease(s) Associated with SMO | |||
| pancreatic cancer |
| Mouse Phenotypes | abnormal tooth morphology |
abnormal incisor morphology |
absent lower incisors |
abnormal molar morphology |
abnormal molar cusp morphology |
fused molars |
abnormal ameloblast morphology |
absent Tomes' process |
abnormal enamel organ morphology |
abnormal stellate reticulum morphology |
abnormal inner dental epithelium morphology |
abnormal outer dental epithelium morphology |
absent enamel cord |
nasal bone hypoplasia |
abnormal face development |
absent tongue |
nasal septum hypoplasia |
abnormal head shape |
embryonic growth retardation |
decreased embryo size |
weight loss |
abnormal head development |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Smobnb/Smobnb | |||||||||||||||||||||||
| Smorgsc2073/Smorgsc2073 | |||||||||||||||||||||||
| Smotm1.1Pab/Smotm1.1Pab | |||||||||||||||||||||||
| Smotm1Amc/Smotm1Amc | |||||||||||||||||||||||
| Tg(Neurod2-Smo*A1)199Jols/Tg(Neurod2-Smo*A1)199Jols | |||||||||||||||||||||||
| Tg(Neurod2-Smo*A2)#Jols/0 | |||||||||||||||||||||||
| Smotm1Amc/Smotm2Amc H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Gt(ROSA)26Sortm1(Smo/EYFP)Amc/? H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Smotm1Amc/Smotm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
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| Smotm1Amc/Smotm2Amc Tg(Fgf15-cre)1Hisa/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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