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Symbol
Name
ID
Smo
smoothened, frizzled class receptor
MGI:108075
Phenotype annotations related to embryo
Darker colors indicate more annotations

Mouse Phenotypes
abnormal sixth pharyngeal arch artery morphology
abnormal vitelline vasculature morphology
increased cardiac neural crest cell number
abnormal neural crest cell apoptosis
abnormal neural crest cell migration
abnormal cardiac neural crest cell migration
abnormal first pharyngeal arch morphology
fused first pharyngeal arch
abnormal embryo development
abnormal developmental patterning
abnormal embryo turning
abnormal direction of embryo turning
incomplete embryo turning
abnormal left-right axis patterning
embryonic growth retardation
decreased embryo size
broad limb buds
abnormal neural fold formation
abnormal neural plate morphology
Availability Mouse Genotype
Smobnb/Smobnb
Smorgsc2073/Smorgsc2073
Smotm1.1Pab/Smotm1.1Pab
Smotm1Amc/Smotm1Amc
Smotm1b(KOMP)Wtsi/Smotm1b(KOMP)Wtsi
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Smotm2Amc/Smotm2.1Amc
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Smotm1Amc/Smotm2Amc
Isl1tm1(cre)Sev/Isl1+  (conditional)
Smotm2Amc/Smotm2.1Amc
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Smotm1Amc/Smotm2Amc
Tg(Fgf15-cre)1Hisa/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory