Symbol Name ID |
Atr
ataxia telangiectasia and Rad3 related MGI:108028 |
Darker colors indicate more annotations |
Mouse Phenotypes | absent oocytes |
abnormal cell cycle |
decreased mitotic index |
increased cellular sensitivity to methylmethanesulfonate |
increased cellular sensitivity to ultraviolet irradiation |
increased fibroblast apoptosis |
increased neuron apoptosis |
increased granulosa cell apoptosis |
increased apoptosis |
decreased granulosa cell proliferation |
increased granulosa cell proliferation |
abnormal neuron proliferation |
decreased cerebellar granule cell precursor proliferation |
decreased cell proliferation |
early cellular replicative senescence |
abnormal DNA replication |
induced chromosome breakage |
spontaneous chromosome breakage |
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Availability | Mouse Genotype | ||||||||||||||||||
Atrtm1Ofc/Atrtm1Ofc | |||||||||||||||||||
Atrtm1Twgl/Atrtm1Twgl | |||||||||||||||||||
Atrtm1Twgl/Atr+ | |||||||||||||||||||
Atrtm2Bal/Atrtm2Bal Tg(Nes-cre)1Kln/0 (conditional) |
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Atrtm2Bal/Atrtm2Bal Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Atrtm1Bal/Atrtm2Bal Ndor1Tg(UBC-cre/ERT2)1Ejb/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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