|
Symbol Name ID |
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit MGI:107940 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Acute myeloid leukemia |
Myeloproliferative disorder |
Myelodysplasia |
Hereditary nonpolyposis colorectal carcinoma |
Neoplasm of the stomach |
Stomach cancer |
Hepatocellular carcinoma |
Retinoblastoma |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Osteosarcoma |
Alveolar cell carcinoma |
Non-small cell lung carcinoma |
Lung adenocarcinoma |
| Disease(s) Associated with EZH2 | |||||||||||||||
| acute myeloid leukemia | |||||||||||||||
| colorectal cancer | |||||||||||||||
| hepatocellular carcinoma | |||||||||||||||
| lung cancer | |||||||||||||||
| myelodysplastic syndrome | |||||||||||||||
| myelofibrosis | |||||||||||||||
| osteosarcoma | |||||||||||||||
| stomach cancer |
| Mouse Phenotypes | neoplasm |
increased leukemia incidence |
increased B cell derived lymphoma incidence |
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| Availability | Mouse Genotype | |||
| Ezh2tm1.1Nesh/Ezh2tm1.1Nesh Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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| Ezh2tm2Sho/Ezh2tm2Sho Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Ezh2tm1.1Nesh/Ezh2+ Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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| Col1a1tm1(CAG-Ezh2*)Meln/Col1a1+ Ighg1tm1(cre)Cgn/Ighg1+ (conditional) |
* | |||
| Ezh2tm2Sho/Ezh2tm2.1Sho Tg(Mx1-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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