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Symbol
Name
ID

Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
MGI:107940

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Splenomegaly	Hepatomegaly	Inguinal hernia	Umbilical hernia	Diastasis recti	Overgrowth	Weight loss
Disease(s) Associated with EZH2	Splenomegaly	Hepatomegaly	Inguinal hernia	Umbilical hernia	Diastasis recti	Overgrowth	Weight loss
myelofibrosis
osteosarcoma
Weaver syndrome

Mouse Phenotypes		increased heart weight	embryonic growth retardation	decreased embryo size	growth/size/body region phenotype	increased body weight	decreased body size	increased growth rate	increased kidney weight	enlarged spleen	increased spleen weight
Availability	Mouse Genotype	increased heart weight	embryonic growth retardation	decreased embryo size	growth/size/body region phenotype	increased body weight	decreased body size	increased growth rate	increased kidney weight	enlarged spleen	increased spleen weight
	Ezh2^em1Jbn/Ezh2^em1Jbn
	Ezh2^tm1Jnw/Ezh2^tm1Jnw
	Ezh2^tm2.1Sho/Ezh2^tm2.1Sho
	Ezh2^em1Jbn/Ezh2⁺
	Ezh2^em1Jiaf/Ezh2⁺				*
	Gt(ROSA)26Sor^{tm4(H1/tetO-RNAi:Ezh2)Arte}/Gt(ROSA)26Sor⁺
	Gt(ROSA)26Sor^{tm5(H1/tetO-RNAi:Ezh2)Arte}/Gt(ROSA)26Sor⁺
	Ezh2^tm1.1Nesh/Ezh2^tm1.1Nesh Cd19^tm1(cre)Cgn/Cd19⁺ (conditional)
	Ezh2^tm2Sho/Ezh2^tm2Sho Tg(Mx1-cre)1Cgn/0 (conditional)
	Ezh2^tm1.1Nesh/Ezh2⁺ Cd19^tm1(cre)Cgn/Cd19⁺ (conditional)
	Ezh2^tm2Sho/Ezh2^tm2.1Sho Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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