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Symbol
Name
ID
Dctn1
dynactin 1
MGI:107745
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Pseudobulbar paralysis
Vocal cord paralysis
Depression
Apathy
Inappropriate behavior
Personality changes
Disinhibition
Hyperorality
Weak voice
Disease(s) Associated with DCTN1
amyotrophic lateral sclerosis type 1
autosomal dominant distal hereditary motor neuronopathy 14
Perry syndrome

Mouse Phenotypes
limb grasping
impaired coordination
short stride length
decreased vertical activity
Availability Mouse Genotype
Dctn1tm1Cai/Dctn1+
Dctn1tm2.1Cai/Dctn1tm2.1Cai
Tg(Thy1-cre)1Vln/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory