Symbol
Name
ID

Phex
phosphate regulating endopeptidase homolog, X-linked
MGI:107489

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes	Bowing of the legs	Femoral bowing	Fibular bowing	Genu valgum	Tibial bowing	Trapezoidal distal femoral condyles	Shortening of the talar neck	Flattening of the talar dome	Cupped metaphyses of hand bones	Metaphyseal irregularity
Disease(s) Associated with PHEX
X-linked dominant hypophosphatemic rickets

Mouse Phenotypes

short humerus

short radius

short ulna

abnormal hindlimb morphology

abnormal acetabulum morphology

decreased diameter of femur

short femur

increased diameter of femur

short fibula

short tibia

abnormal patella morphology

short hindlimb

abnormal limb bone morphology

abnormal limb long bone morphology

camptomelia

abnormal caudal vertebrae morphology

small caudal vertebrae

abnormal tail development

short tail

Availability

Mouse Genotype

Phex^Hyp/Phex^Hyp

Phex^Mhdabap012/Phex^Mhdabap012

Phex^Ska1/Phex^Ska1

Phex^Hpr/Phex⁺

Phex^Hyp-2J/Phex⁺

Phex^Hyp-Duk/Phex⁺

Phex^Hyp/Phex⁺

Phex^m1Jrt/Phex⁺

Phex^Pug/Phex⁺

Phex^Ska1/Phex⁺

Phex^Hpr/Y

Phex^Hyp-2J/Y

Phex^Hyp-Duk/Y

Phex^Hyp/Y

Phex^m1Jrt/Y

Phex^Pug/Y

Phex^Ska1/Y

Phex^tm1.2Mkd/Y

Phex^tm1.1Mkd/Y
Tg(BGLAP-cre)1Clem/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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