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Symbol Name ID |
Pitx1
paired-like homeodomain transcription factor 1 MGI:107374 |
| Darker colors indicate more annotations |
| Human Phenotypes | Enlarged cisterna magna |
Preaxial foot polydactyly |
Mirror image foot polydactyly |
Absent tibia |
Patellar hypoplasia |
Popliteal pterygium |
| Disease(s) Associated with PITX1 | ||||||
| clubfoot |
| Mouse Phenotypes | abnormal Meckel's cartilage morphology |
small mandible |
short mandible |
micrognathia |
abnormal middle ear ossicle morphology |
absent gonial bone |
fused phalanges |
abnormal tarsal bone morphology |
abnormal femur morphology |
short femur |
abnormal fibula morphology |
abnormal tibia morphology |
short tibia |
absent patella |
absent sesamoid bone of gastrocnemius |
abnormal long bone epiphyseal plate morphology |
increased width of hypertrophic chondrocyte zone |
abnormal pelvic girdle bone morphology |
absent ilium |
small ischium |
small pubis |
vertebral transformation |
decreased bone volume |
abnormal cartilage morphology |
abnormal joint morphology |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||
| Pitx1tm1Jdr/Pitx1tm1Jdr | ||||||||||||||||||||||||||
| Pitx1tm1Rsd/Pitx1tm1Rsd | ||||||||||||||||||||||||||
| Pitx1em1(IMPC)Wtsi/Pitx1+ | ||||||||||||||||||||||||||
| Pitx1tm1Rsd/Pitx1+ | ||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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