Symbol
Name
ID

Mttp
microsomal triglyceride transfer protein
MGI:106926

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Abetalipoproteinemia	Increased LDL cholesterol concentration	Decreased resting energy expenditure	Hepatic steatosis
Disease(s) Associated with MTTP	Abetalipoproteinemia	Increased LDL cholesterol concentration	Decreased resting energy expenditure	Hepatic steatosis
abetalipoproteinemia
familial hypercholesterolemia
metabolic dysfunction-associated steatotic liver disease
obesity

Mouse Phenotypes

abnormal circulating lipid level

abnormal circulating cholesterol level

decreased circulating HDL cholesterol level

decreased circulating LDL cholesterol level

decreased circulating VLDL cholesterol level

decreased circulating cholesterol level

decreased circulating triglyceride level

decreased circulating VLDL triglyceride level

abnormal circulating protein level

abnormal lipid homeostasis

increased liver cholesterol level

abnormal lipid level

abnormal triglyceride level

increased liver triglyceride level

Availability

Mouse Genotype

Mttp^tm1Sgy/Mttp^tm1Sgy

Mttp^tm1Sgy/Mttp⁺

Mttp^tm1Chan/Mttp^tm1Chan (conditional)

Mttp^tm2Sgy/Mttp^tm2Sgy
Tg(Mx1-cre)1Cgn/Tg(Mx1-cre)1Cgn (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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