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Symbol Name ID |
Hif1a
hypoxia inducible factor 1, alpha subunit MGI:106918 |
| Darker colors indicate more annotations |
| Human Phenotypes | Type II diabetes mellitus |
Insulin resistance |
| Disease(s) Associated with HIF1A | ||
| type 2 diabetes mellitus |
| Mouse Phenotypes | pericardial effusion |
abnormal milk sodium level |
decreased susceptibility to diet-induced obesity |
decreased susceptibility to induced hypothermia |
decreased circulating glucose level |
decreased circulating insulin level |
increased circulating creatine kinase level |
cyanosis |
abnormal body temperature |
increased energy expenditure |
increased oxygen consumption |
hypoxia |
increased respiratory quotient |
abnormal glucose homeostasis |
abnormal gluconeogenesis |
improved glucose tolerance |
decreased liver glycogen level |
increased insulin sensitivity |
increased bile salt level |
abnormal cytokine level |
abnormal metabolism |
abnormal exercise endurance |
abnormal physiological response to xenobiotic |
decreased susceptibility to xenobiotic induced morbidity/mortality |
decreased physiological sensitivity to xenobiotic |
decreased susceptibility to ischemic brain injury |
increased susceptibility to ischemic brain injury |
increased cerebral infarct size |
delayed wound healing |
increased susceptibility to injury |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Hif1atm1Jhu/Hif1atm1Jhu | |||||||||||||||||||||||||||||||
| Hif1atm1Kats/Hif1atm1Kats | |||||||||||||||||||||||||||||||
| Hif1atm1Pec/Hif1atm1Pec | |||||||||||||||||||||||||||||||
| Hif1atm1Rsjo/Hif1atm1Rsjo | |||||||||||||||||||||||||||||||
| Hif1atm2Rsjo/Hif1atm2Rsjo | |||||||||||||||||||||||||||||||
| Hif1atm1Stom/Hif1atm1Stom Tg(Vil1-cre)20Syr/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Ckmm-cre)5Khn/? (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(MMTV-cre)1Mam/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Tek-cre)1Ywa/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Myl2tm1(cre)Krc/Myl2+ (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Camk2a-cre)2Szi/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo (conditional) | |||||||||||||||||||||||||||||||
| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(Camk2a-cre)1Szi/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Hif1atm3Rsjo/Hif1atm3Rsjo Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1Tg(Alb-cre)21Mgn (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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