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Symbol
Name
ID
Hif1a
hypoxia inducible factor 1, alpha subunit
MGI:106918
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
abnormal vascular regression
abnormal vascular endothelial cell migration
decreased vascular endothelial cell proliferation
abnormal cell physiology
increased cellular sensitivity to gamma-irradiation
increased embryonic tissue cell apoptosis
increased lens fiber apoptosis
decreased neuron apoptosis
increased apoptosis
impaired macrophage chemotaxis
abnormal leukocyte migration
abnormal neural crest cell migration
decreased cell proliferation
decreased hepatocyte proliferation
early cellular replicative senescence
Availability Mouse Genotype
Hif1atm1Jhu/Hif1atm1Jhu
Hif1atm1Pec/Hif1atm1Pec
Hif1atm1Rsjo/Hif1atm1Rsjo
Hif1atm2Rsjo/Hif1atm2Rsjo
Hif1atm1Rsjo/Hif1a+
Hif1atm3Rsjo/Hif1atm3Rsjo
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Tek-cre)1Ywa/0  (conditional)
Hif1atm3Rsjo/Hif1atm3Rsjo  (conditional)
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Pax6-cre,GFP)1Pgr/0  (conditional)
Ccl17tm2.1(cre)Ifo/Ccl17+
Hif1atm3Rsjo/Hif1atm3Rsjo  (conditional)
Hif1atm3Rsjo/Hif1atm3Rsjo
Tg(Itgax-cre)1-1Reiz/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory