Symbol
Name
ID

Dusp1
dual specificity phosphatase 1
MGI:105120

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

homeostasis/metabolism phenotype

decreased susceptibility to diet-induced obesity

decreased circulating cholesterol level

decreased circulating free fatty acids level

decreased circulating triglyceride level

increased circulating interferon-gamma level

increased circulating interleukin-10 level

increased circulating interleukin-6 level

increased circulating tumor necrosis factor level

abnormal circulating alanine transaminase level

decreased circulating alanine transaminase level

increased blood urea nitrogen level

decreased body temperature

increased energy expenditure

pulmonary edema

abnormal nitric oxide homeostasis

increased respiratory quotient

increased prostaglandin level

abnormal chemokine level

abnormal interleukin level

increased hepatic glucose production

increased susceptibility to xenobiotic induced morbidity/mortality

Availability

Mouse Genotype

Dusp1^{tm1(KOMP)Wtsi}/Dusp1^{tm1(KOMP)Wtsi}

Dusp1^tm1Brv/Dusp1^tm1Brv

Dusp1^tm1Lex/Dusp1^tm1Lex

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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