Symbol
Name
ID

Gpx3
glutathione peroxidase 3
MGI:105102

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Increased circulating IgA level

Increased circulating IgG level

Decreased circulating antibody level

Paraproteinemia

Hypercalcemia

Elevated circulating creatinine concentration

Hyperproteinemia

Type II diabetes mellitus

Insulin resistance

Pleural effusion

Abnormality of vitamin B12 metabolism

Increased level of L-fucose in urine

Amyloidosis

Disease(s) Associated with GPX3

multiple myeloma

stomach cancer

type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	increased platelet aggregation	abnormal blood homeostasis	increased susceptibility to induced thrombosis	decreased bleeding time	impaired glucose tolerance	abnormal selenium level	decreased glutathione peroxidase activity	decreased susceptibility to ischemic brain injury	decreased cerebral infarct size
Availability	Mouse Genotype	homeostasis/metabolism phenotype	increased platelet aggregation	abnormal blood homeostasis	increased susceptibility to induced thrombosis	decreased bleeding time	impaired glucose tolerance	abnormal selenium level	decreased glutathione peroxidase activity	decreased susceptibility to ischemic brain injury	decreased cerebral infarct size
	Gpx3^tm1Hjco/Gpx3^tm1Hjco	*
	Gpx3^tm1Jlos/Gpx3^tm1Jlos
	Gpx3^{tm1b(KOMP)Wtsi}/Gpx3⁺
	Gpx3^tm1Jlos/Gpx3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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