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Symbol Name ID |
Gpx1
glutathione peroxidase 1 MGI:104887 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
| Disease(s) Associated with GPX1 | ||||
| multiple myeloma |
| Mouse Phenotypes | myocardium necrosis |
abnormal cell morphology |
abnormal cell cycle |
decreased cellular sensitivity to gamma-irradiation |
increased cellular sensitivity to oxidative stress |
increased cellular sensitivity to hydrogen peroxide |
increased neuron apoptosis |
cellular necrosis |
decreased cell proliferation |
abnormal mitochondrial physiology |
oxidative stress |
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| Availability | Mouse Genotype | |||||||||||
| Gpx1tm1Kola/Gpx1tm1Kola | ||||||||||||
| Gpx1tm1Mgr/Gpx1tm1Mgr | ||||||||||||
| Gpx1tm1Ysh/Gpx1tm1Ysh | ! | |||||||||||
| Tg(Gpx1)41Dkd/0 | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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