Symbol
Name
ID

Lta
lymphotoxin A
MGI:104797

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes

Abnormality of chromosome stability

Chromosome breakage

Abnormality of metabolism/homeostasis

Decreased level of 1,5 anhydroglucitol in serum

Increased LDL cholesterol concentration

Hypercholesterolemia

Hypertriglyceridemia

Elevated circulating hepatic transaminase concentration

Hyperglycemia

Glucose intolerance

Diabetes mellitus

Type II diabetes mellitus

Impaired glucose tolerance

Insulin resistance

Elevated sweat chloride

Ketoacidosis

Dehydration

Hypercalciuria

Increased circulating free T3

Increased circulating free T4 concentration

Decreased thyroid-stimulating hormone level

Disease(s) Associated with LTA

coronary artery disease

cystic fibrosis

Graves' disease

Sjogren's syndrome

systemic scleroderma

type 1 diabetes mellitus

type 2 diabetes mellitus

Mouse Phenotypes		increased susceptibility to diet-induced obesity	decreased circulating interferon-gamma level	abnormal circulating tumor necrosis factor level	increased bronchoconstrictive response	increased susceptibility to injury
Availability	Mouse Genotype	increased susceptibility to diet-induced obesity	decreased circulating interferon-gamma level	abnormal circulating tumor necrosis factor level	increased bronchoconstrictive response	increased susceptibility to injury
	Lta/Tnf^tm1Eug/Lta/Tnf^tm1Eug
	Lta^{tm1.1(KOMP)Vlcg}/Lta^{tm1.1(KOMP)Vlcg}
	Lta^tm1.1Sned/Lta^tm1.1Sned

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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