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Symbol
Name
ID
Gpx4
glutathione peroxidase 4
MGI:104767
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Short neck
Rhizomelia
Rhizomelic arm shortening
Disproportionate short stature
Disease(s) Associated with GPX4
spondylometaphyseal dysplasia Sedaghatian type

Mouse Phenotypes
decreased embryo size
decreased body weight
weight loss
cachexia
Availability Mouse Genotype
Gpx4tm1Yana/Gpx4tm1Yana
Gpx4tm1.1Qra/Gpx4tm1.1Qra
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+  (conditional)
Gpx4tm1Yana/Gpx4tm1Yana
Tg(Gpx4)#Yana/0
Tg(Pgk2-cre)24Shb/0  (conditional)
Gpx4tm2Marc/Gpx4tm2Marc
Tg(Camk2a-cre)2Gsc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory