Symbol Name ID |
Lep
leptin MGI:104663 |
Darker colors indicate more annotations |
Human Phenotypes | Accelerated skeletal maturation |
Osteoporosis |
Disease(s) Associated with LEP | ||
congenital leptin deficiency | ||
osteoporosis |
Mouse Phenotypes | abnormal osteoclast differentiation |
short humerus |
short femur |
short tibia |
abnormal long bone epiphyseal plate morphology |
abnormal long bone epiphyseal plate proliferative zone |
abnormal long bone hypertrophic chondrocyte zone |
decreased length of long bones |
abnormal bone marrow morphology |
decreased bone mass |
increased bone mass |
osteopetrosis |
abnormal skeleton development |
abnormal bone ossification |
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Availability | Mouse Genotype | ||||||||||||||
Lepob/Lepob | |||||||||||||||
Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu | |||||||||||||||
Leptm1Kry/Leptm1Kry | |||||||||||||||
Lepob/Lep+ | |||||||||||||||
Tg(Apcs-Lep)1Yog/0 | |||||||||||||||
Tg(Apoe-Lep)1Kry/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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