|
Symbol Name ID |
Lep
leptin MGI:104663 |
| Darker colors indicate more annotations |
| Human Phenotypes | Polyphagia |
Addictive alcohol use |
| Disease(s) Associated with LEP | ||
| alcohol dependence | ||
| congenital leptin deficiency |
| Mouse Phenotypes | abnormal behavior |
decreased exploration in new environment |
abnormal eating behavior |
abnormal food intake |
decreased food intake |
increased food intake |
polyphagia |
increased anxiety-related response |
decreased grip strength |
decreased vertical activity |
decreased locomotor activity |
abnormal sleep pattern |
abnormal frequency of paradoxical sleep |
fragmentation of sleep/wake states |
abnormal pain threshold |
allodynia |
hyperalgesia |
increased thermal nociceptive threshold |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Lepm1Yst/Lepm1Yst | |||||||||||||||||||
| Lepob/Lepob | |||||||||||||||||||
| Lepob/Lepob Tg(Npy-MAPT/Sapphire)1Rck/0 |
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| Lepob/Lepob Tg(Pomc-MAPT/Topaz)1Rck/0 |
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| Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu | |||||||||||||||||||
| Tg(Apcs-Lep)1Yog/0 | |||||||||||||||||||
| Tg(Apoe-Lep)1Kry/0 | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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