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Symbol
Name
ID
Cnr1
cannabinoid receptor 1
MGI:104615
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Negativism
Disease(s) Associated with CNR1
schizophrenia

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
impaired behavioral response to morphine
increased behavioral withdrawal response
impaired behavioral response to addictive substance
increased susceptibility to pharmacologically induced seizures
impaired behavioral response to xenobiotic
abnormal learning/memory/conditioning
abnormal active avoidance behavior
impaired conditioned place preference behavior
abnormal cued conditioning behavior
impaired cued conditioning behavior
decreased exploration in new environment
increased exploration in new environment
abnormal food intake
increased aggression towards mice
abnormal depression-related behavior
anhedonia
decreased thigmotaxis
increased anxiety-related response
abnormal response to novel object
abnormal impulsive behavior control
decreased vertical activity
decreased locomotor activity
increased locomotor activity
hyperactivity
increased chemical nociceptive threshold
increased chemically-elicited antinociception
hypoalgesia
increased thermal nociceptive threshold
abnormal social/conspecific interaction behavior
catalepsy
Availability Mouse Genotype
Cnr1tm1.1Kpm/Cnr1tm1.1Kpm
Cnr1tm1.1Ltz/Cnr1tm1.1Ltz *
Cnr1tm1Dgen/Cnr1tm1Dgen
Cnr1tm1Map/Cnr1tm1Map
Cnr1tm1Ojm/Cnr1tm1Ojm
Cnr1tm1Zim/Cnr1tm1Zim
Cnr1tm2Ltz/Cnr1tm2Ltz
Cnr1tm1.1(KOMP)Vlcg/Cnr1+
Cnr1tm1.1Ltz/Cnr1+
Cnr1tm1.1Pcn/Cnr1tm1.1Pcn
Tg(Phox2b-cre)1Jke/0  (conditional)
*
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz
Tg(Camk2a-cre)2Gsc/0  (conditional)
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz
Tg(Camk2a-cre)2Gsc/?  (conditional)
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz  (conditional)
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz
Neurod6tm1(cre)Kan/Neurod6+  (conditional)
Cnr1tm1.2Ltz/Cnr1tm1.2Ltz
Tg(dlx5a-cre)1Mekk/?  (conditional)
*
Cnr1tm2Ltz/Cnr1tm2.1Ltz
Neurod6tm1(cre)Kan/Neurod6+  (conditional)
* !

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory