|
Symbol Name ID |
Brca1
breast cancer 1, early onset MGI:104537 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Myelodysplasia |
Neoplasia of the nasopharynx |
Breast carcinoma |
Hereditary nonpolyposis colorectal carcinoma |
Colon cancer |
Neoplasm of the stomach |
Stomach cancer |
Neoplasm of the liver |
Pancreatic adenocarcinoma |
Prostate cancer |
Dysgerminoma |
Ovarian carcinoma |
Ovarian papillary adenocarcinoma |
Cervix cancer |
Uterine leiomyosarcoma |
Renal cell carcinoma |
Bladder neoplasm |
Transitional cell carcinoma of the bladder |
Neoplasm |
Melanoma |
| Disease(s) Associated with BRCA1 | ||||||||||||||||||||
| breast cancer | ||||||||||||||||||||
| cervical cancer | ||||||||||||||||||||
| colorectal cancer | ||||||||||||||||||||
| Fanconi anemia | ||||||||||||||||||||
| nasopharynx carcinoma | ||||||||||||||||||||
| ovarian cancer | ||||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||||
| prostate cancer | ||||||||||||||||||||
| stomach cancer | ||||||||||||||||||||
| urinary bladder cancer |
| Mouse Phenotypes | neoplasm |
increased mouth tumor incidence |
increased salivary adenocarcinoma incidence |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
increased T cell derived lymphoma incidence |
increased skin tumor incidence |
increased liver tumor incidence |
increased lymphoma incidence |
increased squamous cell carcinoma incidence |
increased incidence of tumors by ionizing radiation induction |
increased tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||
| Brca1tm2Arge/Brca1tm2Arge | |||||||||||||
| Brca1tm2Rjbr/Brca1tm2Rjbr | |||||||||||||
| Brca1tm3.1Rjbr/Brca1tm3.1Rjbr | * | ||||||||||||
| Brca1tm5.1Cxd/Brca1tm5.1Cxd | |||||||||||||
| Brca1tm1Bhk/Brca1+ | |||||||||||||
| Brca1tm2Arge/Brca1tm3.1Rjbr | * | ||||||||||||
| Brca1tm1Aash/Brca1tm1Aash Tg(LGB-cre)74Acl/0 (conditional) |
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| Brca1tm1Brn/Brca1tm1Brn Tg(KRT14-cre)8Brn/0 (conditional) |
* | ||||||||||||
| Brca1tm1Thl/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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| Brca1tm2Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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| Brca1tm2Mak/Brca1tm2Mak Tg(Lck-cre)548Jxm/? (conditional) |
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| Brca1tm2Mak/Brca1tm2Mak Tg(Wap-cre)11738Mam/? (conditional) |
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| Brca1tm1Arge/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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| Brca1tm1Cxd/Brca1tm2Cxd Tg(Wap-cre)11738Mam/0 (conditional) |
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| Brca1tm1Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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| Brca1tm1Cxd/Brca1tm2Cxd Tg(KRT5-cre)5132Jlj/0 (conditional) |
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| Brca1tm2.1Cxd/Brca1tm3.1Rjbr Waptm1(cre)Arge/Wap+ (conditional) |
* | ||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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