Symbol Name ID |
Brca1
breast cancer 1, early onset MGI:104537 |
Darker colors indicate more annotations |
Human Phenotypes | Breast carcinoma |
Jaundice |
Abnormality of skin pigmentation |
Irregular hyperpigmentation |
Multiple cafe-au-lait spots |
Hypopigmented skin patches |
Disease(s) Associated with BRCA1 | ||||||
breast cancer | ||||||
Fanconi anemia | ||||||
ovarian cancer | ||||||
pancreatic cancer |
Mouse Phenotypes | decreased subcutaneous adipose tissue amount |
increased keratinocyte proliferation |
decreased mammary gland epithelial cell proliferation |
increased mammary gland epithelial cell proliferation |
abnormal mammary gland development |
abnormal branching of the mammary ductal tree |
abnormal involution of the mammary gland |
abnormal mammary gland growth during pregnancy |
abnormal mammary gland duct morphology |
abnormal mammary gland lobule morphology |
mammary gland alveolar hyperplasia |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
mammary gland hyperplasia |
increased mammary gland apoptosis |
dermatitis |
abnormal coat/hair pigmentation |
abnormal hair growth |
abnormal hair follicle morphology |
decreased hair follicle number |
abnormal epidermal layer morphology |
abnormal skin pigmentation |
increased skin tumor incidence |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Brca1tm2Arge/Brca1tm2Arge | ||||||||||||||||||||||||
Brca1tm5.1Cxd/Brca1tm5.1Cxd | ||||||||||||||||||||||||
Brca1tm1Bhk/Brca1+ | ||||||||||||||||||||||||
Brca1tm1Aash/Brca1tm1Aash Tg(LGB-cre)74Acl/0 (conditional) |
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Brca1tm1Thl/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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Brca1tm2Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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Brca1tm2Mak/Brca1tm2Mak Tg(Wap-cre)11738Mam/? (conditional) |
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Brca1tm1Arge/Brca1tm1Thl Waptm1(cre)Arge/0 (conditional) |
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Brca1tm1Cxd/Brca1tm2Cxd Tg(Wap-cre)11738Mam/0 (conditional) |
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Brca1tm1Cxd/Brca1tm2Cxd Tg(MMTV-cre)4Mam/0 (conditional) |
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Brca1tm1Cxd/Brca1tm2Cxd Tg(KRT5-cre)5132Jlj/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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