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Symbol
Name
ID
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
MGI:103562
Phenotype annotations related to growth/size/body
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Increased waist to hip ratio
Increased body mass index
Small for gestational age
Obesity
Intrauterine growth retardation
Disease(s) Associated with HSD11B1
cortisone reductase deficiency 2
pre-eclampsia
type 2 diabetes mellitus

Mouse Phenotypes
growth/size/body region phenotype
decreased susceptibility to weight gain
Availability Mouse Genotype
Hsd11b1tm1.1Awhi/Hsd11b1tm1.1Awhi *
Hsd11b1tm1.2Tuck/Hsd11b1tm1.2Tuck
Hsd11b1tm1.2Awhi/Hsd11b1tm1.2Awhi
Tg(Nes-cre)1Kln/0  (conditional)
*
Hsd11b1tm1Ggla/Hsd11b1tm1Ggla
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory