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Symbol
Name
ID
Vhl
von Hippel-Lindau tumor suppressor
MGI:103223
Phenotype annotations related to cellular
Darker colors indicate more annotations

Mouse Phenotypes
oligozoospermia
multinucleated giant male germ cells
decreased mitochondrial number
increased mesangial cell number
decreased renal tubule apoptosis
embryo tissue necrosis
focal hepatic necrosis
increased keratinocyte proliferation
decreased cell proliferation
increased hepatocyte proliferation
abnormal intracellular organelle physiology
Availability Mouse Genotype
Vhltm1.1Whkr/Vhltm1.1Whkr
Vhltm1Jae/Vhltm1Jae
Vhltm1Lss/Vhltm1.1Lss
Vhltm1Jae/Vhltm1Jae
Tg(KRT14-cre)1Ipc/0  (conditional)
Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(Myh6-cre)2182Mds/0  (conditional)
Vhltm1Jae/Vhltm1Jae
Tg(NPHS2-cre)295Lbh/?  (conditional)
Vhltm1Lss/Vhltm1.1Lss
Tg(ACTB-cre)1Tes/0  (conditional)
Vhltm1Lss/Vhltm1.1Lss
Tg(CAG-cre/Esr1*)1Lbe/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory