Symbol
Name
ID

Vegfa
vascular endothelial growth factor A
MGI:103178

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Thickened nuchal skin fold	Splenomegaly	Hepatosplenomegaly	Abnormal abdomen morphology	Tall stature	Increased body mass index	Small for gestational age	Weight loss	Intrauterine growth retardation
Disease(s) Associated with VEGFA	Thickened nuchal skin fold	Splenomegaly	Hepatosplenomegaly	Abnormal abdomen morphology	Tall stature	Increased body mass index	Small for gestational age	Weight loss	Intrauterine growth retardation
chronic myeloid leukemia
Graves' disease
multiple myeloma
pre-eclampsia
pseudoxanthoma elasticum

Mouse Phenotypes

enlarged heart

absent incisors

abnormal palatal mesenchymal cell proliferation

abnormal secondary palate development

abnormal palatal shelf bone ossification

abnormal palatal shelf elevation

palatal shelves fail to meet at midline

decreased palatal shelf size

palatal shelf hypoplasia

cleft palate

decreased body weight

slow postnatal weight gain

decreased body size

postnatal growth retardation

Availability

Mouse Genotype

Vegfa^tm1.1Nagy/Vegfa^tm1.1Nagy

Vegfa^tm1Pec/Vegfa^tm1Pec

Vegfa^tm2Pec/Vegfa^tm2Pec

Vegfa^tm4Pec/Vegfa^tm4Pec

Tg(Neph1-Vegfa)1Seq/0

Vegfa^tm2Gne/Vegfa^tm2Gne
Tg(Mx1-cre)1Cgn/0 (conditional)

Vegfa^tm2Gne/Vegfa^tm2Gne
Tg(Tnnt2-cre)5Blh/0 (conditional)

Vegfa^tm2Gne/Vegfa^tm2Gne
E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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