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Symbol
Name
ID 		Fosl2
fos-like antigen 2
MGI:102858
Phenotype annotations related to skeleton
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
skeleton phenotype
abnormal osteoclast differentiation
abnormal osteoblast physiology
increased osteoclast cell number
abnormal osteoclast morphology
abnormal osteoclast physiology
decreased width of hypertrophic chondrocyte zone
abnormal long bone epiphysis morphology
kyphosis
abnormal vertebrae morphology
abnormal vertebrae development
abnormal vertebral arch morphology
decreased bone mineral density
decreased bone volume
increased bone volume
abnormal osteoblast morphology
decreased bone trabecula number
increased bone trabecula number
decreased trabecular bone thickness
increased trabecular bone thickness
increased bone mass
abnormal cartilage morphology
abnormal chondrocyte morphology
abnormal chondrocyte differentiation
abnormal skeleton development
decreased bone mineralization
delayed endochondral bone ossification
decreased bone ossification
increased bone ossification
increased bone resorption
Availability Mouse Genotype
Fosl2tm1Wag/Fosl2tm1Wag
Fosl2tm2.1Wag/Fosl2tm2.1Wag
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
Tg(H2-K-Fosl2,-EGFP)13Wag/0
Fosl2tm2Wag/Fosl2tm2Wag
Tg(COL2A1-cre)1Wag/0  (conditional)
Fosl2tm2Wag/Fosl2tm2Wag
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Fosl2tm2Wag/Fosl2tm2Wag
Meox2tm1(cre)Sor/Meox2+  (conditional)		 *
Fosl2tm2Wag/Fosl2tm2Wag
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory