Symbol
Name
ID

Tsc2
TSC complex subunit 2
MGI:102548

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Abdominal pain	Back pain	Lethargy	Autism	Attention deficit hyperactivity disorder	Fatigue	Chest pain
Disease(s) Associated with TSC2	Abdominal pain	Back pain	Lethargy	Autism	Attention deficit hyperactivity disorder	Fatigue	Chest pain
lymphangioleiomyomatosis
medulloblastoma
tuberous sclerosis 2

Mouse Phenotypes

behavior/neurological phenotype

abnormal contextual conditioning behavior

abnormal motor learning

abnormal spatial learning

decreased coping response

abnormal response to novel object

abnormal response to social novelty

ataxia

impaired coordination

abnormal gait

increased vertical activity

abnormal social investigation

seizures

environmentally induced seizures

Availability

Mouse Genotype

Tsc2^tm1Djk/Tsc2⁺

Tsc2^tm1Tno/Tsc2⁺

Tg(CMV-Tsc2*)1Arbi/0

Tsc2^tm1.1Kcess/Tsc2^tm1.1Kcess
Emx1^tm1(cre)Krj/Emx1⁺ (conditional)

Tg(GFAP-cre)8Gtm/0
Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg (conditional)

Tg(Pcp2-cre)2Mpin/0
Tsc2^tm1.1Mjg/Tsc2^tm1.1Mjg (conditional)

Tg(Pcp2-cre)2Mpin/0
Tsc2^tm1.1Mjg/Tsc2^tm1.2Mjg (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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