Symbol
Name
ID

Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

vision/eye phenotype

impaired pupillary reflex

abnormal visual pursuit

increased retina apoptosis

abnormal optic nerve innervation

decreased retina ganglion cell number

increased amacrine cell number

abnormal retina ganglion cell morphology

retina ganglion cell degeneration

abnormal optic nerve morphology

abnormal optic disk morphology

optic nerve degeneration

optic nerve atrophy

optic nerve hypoplasia

abnormal retina morphology

thin retina ganglion layer

thin retina inner nuclear layer

abnormal retina nerve fiber layer morphology

thin retina outer nuclear layer

decreased total retina thickness

retina hypoplasia

abnormal eye electrophysiology

abnormal vision

Availability

Mouse Genotype

Pou4f2^tm1Nat/Pou4f2^tm1Nat

Pou4f2^tm1Rsd/Pou4f2^tm1Rsd

Pou4f2^tm3Whk/Pou4f2^tm3Whk

Pou4f2^tm1(ALPP)Whk/Pou4f2^tm2Whk

Pou4f2^{tm1(Pou4f1)Gan}/Pou4f2^tm2Whk

Pou4f2^tm2.1Gan/Pou4f2^tm2.1Gan
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Pou4f2^tm4(DTA)Whk/Pou4f2^tm4(DTA)Whk
Tg(Six3-cre)69Frty/? (conditional)

Opn4^{tm1.1(cre)Saha}/Opn4⁺
Pou4f2^tm4(DTA)Whk/Pou4f2⁺
Tg(CAG-Bgeo/ALPP)1Lbe/0 (conditional)

Opn4^{tm1.1(cre)Saha}/Opn4⁺
Pou4f2^tm4(DTA)Whk/Pou4f2⁺ (conditional)

Pou4f2^tm1Nat/Pou4f2^tm2.1Nat
Tg(Pax6-cre,GFP)2Pgr/? (conditional)

Pou4f2^tm4(DTA)Whk/Pou4f2⁺
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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