Symbol
Name
ID

Mmp14
matrix metallopeptidase 14 (membrane-inserted)
MGI:101900

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Coarse facial features	Gingival overgrowth
Disease(s) Associated with MMP14	Coarse facial features	Gingival overgrowth
Winchester syndrome

Mouse Phenotypes

abnormal craniofacial morphology

abnormal cranial suture morphology

abnormal cranium morphology

abnormal Meckel's cartilage morphology

small cranial cavity

abnormal cranial vertex morphology

decreased cranium height

decreased cranium length

decreased cranium width

abnormal neurocranium morphology

abnormal fontanelle morphology

abnormal interparietal bone morphology

abnormal parietal bone morphology

abnormal orbit morphology

abnormal incisor morphology

short lower incisors

abnormal upper incisor morphology

short upper incisors

short incisors

abnormal tooth development

delayed tooth eruption

malocclusion

small mandible

short mandible

short maxilla

domed cranium

short snout

round head

small ears

Availability

Mouse Genotype

Mmp14^m1Btlr/Mmp14^m1Btlr

Mmp14^sabe/Mmp14^sabe

Mmp14^tm1Hbh/Mmp14^tm1Hbh

Mmp14^tm1Ktry/Mmp14^tm1Ktry

Mmp14^tm1Stjw/Mmp14^tm1Stjw
Twist2^{tm1.1(cre)Dor}/Twist2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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