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Symbol
Name
ID
Ppard
peroxisome proliferator activator receptor delta
MGI:101884
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Insulin resistance
Disease(s) Associated with PPARD
type 2 diabetes mellitus

Mouse Phenotypes
decreased aerobic running capacity
increased cardiac muscle glycogen level
abnormal response to cardiac infarction
decreased myocardial infarct size
increased circulating VLDL cholesterol level
increased circulating triglyceride level
abnormal circulating protein level
abnormal energy expenditure
impaired glucose tolerance
insulin resistance
decreased liver cholesterol level
decreased cholesterol level
abnormal lipid level
increased fatty acids level
decreased liver triglyceride level
abnormal response to exercise
increased incidence of tumors by chemical induction
delayed wound healing
Availability Mouse Genotype
Ppardtm1Dsvg/Ppardtm1Dsvg
Ppardtm1Jps/Ppardtm1Jps
Ppardtm1Wwah/Ppard+
Tg(Ckm-Ppard)MEDpk/0
Tg(Myh6-Ppard)HEDpk/0
Ppardtm1Mtz/Ppardtm1Mtz
Tg(KRT14-cre)1Ipc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory