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Symbol
Name
ID

Cfl2
cofilin 2, muscle
MGI:101763

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Weakness of facial musculature

Knee flexion contracture

Shoulder girdle muscle weakness

Limb muscle weakness

Hypotonia

Frequent falls

Muscle weakness

Neck muscle weakness

Gowers sign

Respiratory insufficiency due to muscle weakness

Nemaline bodies

Fatty replacement of skeletal muscle

Minicore myopathy

Disease(s) Associated with CFL2

nemaline myopathy 7

Mouse Phenotypes		abnormal sarcomere morphology	abnormal Z line morphology	abnormal skeletal muscle fiber morphology	skeletal muscle fiber degeneration	abnormal skeletal muscle morphology	abnormal skeletal muscle fiber type ratio	muscle weakness
Availability	Mouse Genotype	abnormal sarcomere morphology	abnormal Z line morphology	abnormal skeletal muscle fiber morphology	skeletal muscle fiber degeneration	abnormal skeletal muscle morphology	abnormal skeletal muscle fiber type ratio	muscle weakness
	Cfl2^tm1.1Itl/Cfl2^tm1.1Itl
	Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Ckmm-cre)5Khn/0 (conditional)
	Cfl2^tm1Itl/Cfl2^tm1Itl Tg(ACTA1-cre)79Jme/0 (conditional)
	Cfl2^tm1Itl/Cfl2^tm1Itl Tg(Mef2c-cre)1Blk/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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