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Symbol
Name
ID

Lyst
lysosomal trafficking regulator
MGI:107448

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Iris hypopigmentation	Ocular albinism	Macular hypoplasia	Abnormality of retinal pigmentation	Strabismus	Nystagmus	Horizontal nystagmus	Rotary nystagmus	Photophobia	Reduced visual acuity
Disease(s) Associated with LYST
Chediak-Higashi syndrome

Mouse Phenotypes

vision/eye phenotype

abnormal eye pigmentation

abnormal choroid pigmentation

abnormal ciliary body pigmentation

abnormal iris pigment epithelium

abnormal iris pigmentation

abnormal retina pigment epithelium morphology

abnormal retina pigmentation

decreased eye pigmentation

abnormal anterior uvea morphology

abnormal iridocorneal angle

abnormal iris morphology

abnormal iris stroma morphology

abnormal eye anterior chamber morphology

abnormal retina morphology

abnormal retina layer morphology

Availability

Mouse Genotype

Lyst^bg-2J/Lyst^bg-2J

Lyst^bg-10J/Lyst^bg-10J

Lyst^bg-16J/Lyst^bg-16J

Lyst^bg-grey/Lyst^bg-grey

Lyst^bg-J/Lyst^bg-J

*

Lyst^bg-Lac/Lyst^bg-Lac

Lyst^bg-slt/Lyst^bg-slt

Lyst^{tm1b(EUCOMM)Wtsi}/Lyst^{tm1b(EUCOMM)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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