Symbol Name ID |
Pou4f2
POU domain, class 4, transcription factor 2 MGI:102524 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | vision/eye phenotype |
impaired pupillary reflex |
abnormal visual pursuit |
increased retina apoptosis |
abnormal optic nerve innervation |
decreased retina ganglion cell number |
increased amacrine cell number |
abnormal retina ganglion cell morphology |
retina ganglion cell degeneration |
abnormal optic nerve morphology |
abnormal optic disk morphology |
optic nerve degeneration |
optic nerve atrophy |
optic nerve hypoplasia |
abnormal retina morphology |
thin retina ganglion layer |
thin retina inner nuclear layer |
abnormal retina nerve fiber layer morphology |
thin retina outer nuclear layer |
decreased total retina thickness |
retina hypoplasia |
abnormal eye electrophysiology |
abnormal vision |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Pou4f2tm1Nat/Pou4f2tm1Nat | ||||||||||||||||||||||||
Pou4f2tm1Rsd/Pou4f2tm1Rsd | ||||||||||||||||||||||||
Pou4f2tm3Whk/Pou4f2tm3Whk | ||||||||||||||||||||||||
Pou4f2tm1(ALPP)Whk/Pou4f2tm2Whk | ||||||||||||||||||||||||
Pou4f2tm1(Pou4f1)Gan/Pou4f2tm2Whk | * | |||||||||||||||||||||||
Pou4f2tm2.1Gan/Pou4f2tm2.1Gan Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
* | |||||||||||||||||||||||
Pou4f2tm4(DTA)Whk/Pou4f2tm4(DTA)Whk Tg(Six3-cre)69Frty/? (conditional) |
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Opn4tm1.1(cre)Saha/Opn4+ Pou4f2tm4(DTA)Whk/Pou4f2+ Tg(CAG-Bgeo/ALPP)1Lbe/0 (conditional) |
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Opn4tm1.1(cre)Saha/Opn4+ Pou4f2tm4(DTA)Whk/Pou4f2+ (conditional) |
* | |||||||||||||||||||||||
Pou4f2tm1Nat/Pou4f2tm2.1Nat Tg(Pax6-cre,GFP)2Pgr/? (conditional) |
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Pou4f2tm4(DTA)Whk/Pou4f2+ Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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