Symbol Name ID |
Wnt4
wingless-type MMTV integration site family, member 4 MGI:98957 |
Darker colors indicate more annotations |
Human Phenotypes | Short neck |
Brachydactyly |
Cubitus valgus |
Shield chest |
Disease(s) Associated with WNT4 | ||||
Mullerian aplasia and hyperandrogenism |
Mouse Phenotypes | decreased chondrocyte proliferation |
abnormal craniofacial bone morphology |
small frontal bone |
small occipital bone |
long incisors |
short nasal bone |
domed cranium |
decreased femoral compact bone area |
increased width of hypertrophic chondrocyte zone |
disorganized long bone epiphyseal plate |
abnormal pubis morphology |
kyphosis |
short lumbar vertebrae |
axial skeleton hypoplasia |
abnormal bone marrow morphology |
decreased areal bone mineral density |
decreased bone mineral density of femur |
decreased bone trabecula number |
decreased trabecular bone mass |
abnormal cartilage morphology |
abnormal chondrocyte morphology |
delayed endochondral bone ossification |
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Availability | Mouse Genotype | ||||||||||||||||||||||
Wnt4tm1.1Bhr/Wnt4tm1.1Bhr Tg(Prrx1-cre)1Cjt/0 (conditional) |
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Gt(ROSA)26Sortm1(Wnt4)Bhr/Gt(ROSA)26Sor+ Tg(Col2a1-cre)1Bhr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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