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Symbol
Name
ID
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
MGI:97530
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Back pain
Disease(s) Associated with PDGFRA
pancreatic cancer

Mouse Phenotypes
impaired ossification of basisphenoid bone
decreased cranium height
abnormal frontal bone morphology
abnormal parietal bone morphology
abnormal nasal bone morphology
absent zygomatic bone
ectopic cranial bone
abnormal nasal capsule morphology
abnormal scapula morphology
acromion hypoplasia
abnormal sternum morphology
absent sternum
wide sternum
abnormal pubis morphology
abnormal rib joint morphology
abnormal rib morphology
rib bifurcation
rib fusion
abnormal thoracic vertebrae morphology
abnormal spine curvature
abnormal cervical vertebrae morphology
abnormal skeleton development
Availability Mouse Genotype
Pdgfratm1Sor/Pdgfratm1Sor
Pdgfratm2Sor/Pdgfratm2Sor
Pdgfratm10(Pdgfra/tor)Sor/Pdgfratm10(Pdgfra/tor)Sor
Pdgfratm9(Pdgfra/Fgfr1)Sor/Pdgfra+
Pdgfratm12.1Sor/Pdgfra+
Pdgfratm8Sor/Pdgfratm8Sor
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Pdgfratm8Sor/Pdgfratm8Sor
Tg(Col2a1-cre)1Rsjo/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory