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Symbol
Name
ID

Mmp2
matrix metallopeptidase 2
MGI:97009

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Medial calcification of large arteries	Medial calcification of medium-sized arteries	Joint hypermobility	Joint stiffness	Abnormal thorax morphology	Abnormal sternum morphology	Kyphosis	Scoliosis	Arthritis	Cerebral calcification	Calcification of falx cerebri
Disease(s) Associated with MMP2	Medial calcification of large arteries	Medial calcification of medium-sized arteries	Joint hypermobility	Joint stiffness	Abnormal thorax morphology	Abnormal sternum morphology	Kyphosis	Scoliosis	Arthritis	Cerebral calcification	Calcification of falx cerebri
pseudoxanthoma elasticum
temporal arteritis

Mouse Phenotypes

abnormal coronal suture morphology

coronal suture sclerosis

abnormal lambdoid suture morphology

lambdoid suture sclerosis

abnormal sagittal suture morphology

sagittal suture sclerosis

abnormal cranium morphology

short mandible

short maxilla

decreased osteoclast cell number

arthritis

decreased length of long bones

abnormal bone structure

decreased bone mineral content

decreased bone mineral density

decreased bone volume

abnormal compact bone morphology

decreased osteoblast cell number

abnormal trabecular bone morphology

abnormal articular cartilage morphology

abnormal skeleton development

Availability

Mouse Genotype

Mmp2^em1(IMPC)Mbp/Mmp2^em1(IMPC)Mbp

Mmp2^tm1Ito/Mmp2^tm1Ito

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23