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Symbol
Name
ID
Kras
Kirsten rat sarcoma viral oncogene homolog
MGI:96680
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Frontal bossing
Prominent occiput
Biparietal narrowing
Plagiocephaly
Micrognathia
Hypoplasia of the zygomatic bone
Dandy-Walker malformation
Macrocephaly
Short neck
Genu valgum
Clinodactyly of the 5th finger
Brachydactyly
Radioulnar synostosis
Abnormal morphology of ulna
Short palm
Genu recurvatum
Cubitus valgus
Flexion contracture
Joint hypermobility
Delayed skeletal maturation
Bone pain
Pathologic fracture
Enlarged thorax
Pectus carinatum
Pectus excavatum
Scoliosis
Vertebral compression fracture
Vertebral segmentation defect
Back pain
Osteopenia
Neoplasm of the skeletal system
Cerebral calcification
Disease(s) Associated with KRAS
cardiofaciocutaneous syndrome
linear nevus sebaceous syndrome
Lynch syndrome
multiple myeloma
Noonan syndrome
oculoectodermal syndrome
pancreatic cancer

Mouse Phenotypes
abnormal cranium morphology
decreased cranium length
increased cranium height
increased cranium width
Availability Mouse Genotype
Krastm4.1Bbd/Krastm4.1Bbd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory