|
Symbol Name ID |
Igf2
insulin-like growth factor 2 MGI:96434 |
| Darker colors indicate more annotations |
| Human Phenotypes | Frontal bossing |
Micrognathia |
Delayed cranial suture closure |
Short distal phalanx of the 5th finger |
Short middle phalanx of the 5th finger |
Clinodactyly of the 5th finger |
Interphalangeal joint erosions |
Swan neck-like deformities of the fingers |
Syndactyly |
Joint swelling |
Joint stiffness |
Delayed skeletal maturation |
Rheumatoid arthritis |
Polyarticular arthritis |
Digital flexor tenosynovitis |
| Disease(s) Associated with IGF2 | |||||||||||||||
| rheumatoid arthritis | |||||||||||||||
| Silver-Russell syndrome |
| Mouse Phenotypes | abnormal osteoblast differentiation |
abnormal osteoclast differentiation |
abnormal tibia morphology |
abnormal skeleton morphology |
abnormal sternum morphology |
abnormal xiphoid process morphology |
abnormal lumbar vertebrae morphology |
abnormal bone marrow cavity morphology |
decreased bone mineral density |
abnormal compact bone lamellar structure |
increased compact bone thickness |
decreased osteoblast cell number |
abnormal bone trabecula morphology |
abnormal cartilage development |
abnormal skeleton development |
delayed bone ossification |
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| Availability | Mouse Genotype | ||||||||||||||||
| Igf2tm1Rob/Igf2+ | |||||||||||||||||
| Igf2tm1Snha/Igf2+ | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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