Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
Darker colors indicate more annotations |
Human Phenotypes | Progressive macrocephaly |
Delayed cranial suture closure |
Back pain |
Osteoma |
Cerebellar calcifications |
Disease(s) Associated with APC | |||||
familial adenomatous polyposis 1 | |||||
medulloblastoma | |||||
pancreatic cancer |
Mouse Phenotypes | enhanced osteoblast differentiation |
abnormal cranium morphology |
absent upper incisors |
abnormal tooth development |
absent teeth |
abnormal mandible morphology |
absent mandible |
acrania |
abnormal humerus morphology |
increased osteosarcoma incidence |
increased osteoma incidence |
scapular bone hypoplasia |
absent sternum |
abnormal rib morphology |
short ribs |
abnormal cartilage development |
abnormal chondrocyte morphology |
abnormal skeleton development |
abnormal bone mineralization |
abnormal endochondral bone ossification |
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Availability | Mouse Genotype | ||||||||||||||||||||
ApcM1Tno/Apc+ | |||||||||||||||||||||
ApcMin/Apctm1Tno | |||||||||||||||||||||
Apctm1.1Tno/Apctm1Tno | |||||||||||||||||||||
Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 (conditional) |
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Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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