Symbol Name ID |
Sp7
Sp7 transcription factor 7 MGI:2153568 |
Darker colors indicate more annotations |
Human Phenotypes | Brachyturricephaly |
Micrognathia |
Wormian bones |
Dentinogenesis imperfecta |
Bowing of the long bones |
Bowing of the arm |
Bowing of the legs |
Hyperextensibility of the finger joints |
Hypermobility of interphalangeal joints |
Recurrent fractures |
Pectus carinatum |
Scoliosis |
Osteoporosis |
Generalized osteoporosis |
Disease(s) Associated with SP7 | ||||||||||||||
osteogenesis imperfecta type 12 |
Mouse Phenotypes | abnormal osteoblast differentiation |
abnormal limb bone morphology |
clavicle hypoplasia |
abnormal axial skeleton morphology |
abnormal rib morphology |
abnormal vertebrae morphology |
abnormal trabecular bone morphology |
abnormal skeleton development |
abnormal bone ossification |
abnormal bone mineralization |
rickets |
failure of endochondral bone ossification |
failure of bone ossification |
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Availability | Mouse Genotype | |||||||||||||
Sp7tm1.1Rnis/Sp7tm1.1Rnis | ||||||||||||||
Sp7tm1Crm/Sp7tm1Crm | ||||||||||||||
Sp7tm1Rnis/Sp7tm1Rnis Tg(Col11a2-cre)1Ntsu/0 (conditional) |
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Sp7tm1Rnis/Sp7tm1Rnis Tg(Col2a1-cre)1Bhr/0 (conditional) |
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Sp7tm1Rnis/Sp7tm1Rnis Tg(Prrx1-cre)1Cjt/0 (conditional) |
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Sox9tm3(cre)Crm/Sox9+ Sp7tm1Crm/Sp7tm2Crm (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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