Symbol
Name
ID

Sp6
trans-acting transcription factor 6
MGI:1932575

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Amelogenesis imperfecta	Enamel hypoplasia
Disease(s) Associated with SP6	Amelogenesis imperfecta	Enamel hypoplasia
amelogenesis imperfecta type 1K

Mouse Phenotypes

abnormal tooth morphology

abnormal incisor morphology

small incisors

supernumerary incisors

abnormal molar cusp morphology

fused molars

supernumerary molars

abnormal tooth color

abnormal tooth development

abnormal ameloblast morphology

abnormal enamel organ morphology

delayed tooth eruption

abnormal tooth mineralization

abnormal tooth hard tissue morphology

abnormal dentin morphology

absent enamel

reduced enamel thickness

supernumerary teeth

abnormal Hertwig epithelial root sheath morphology

short tooth root

brittle teeth

fused teeth

microdontia

Availability

Mouse Genotype

Sp6^{em1(IMPC)Ccpcz}/Sp6^{em1(IMPC)Ccpcz}

Sp6^tm1.1Ibmm/Sp6^tm1.1Ibmm

Sp6^tm1Yoya/Sp6^tm1Yoya

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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