Symbol
Name
ID

Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
MGI:1330223

Phenotype annotations related to skeleton

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Bowing of the legs	Brachydactyly	Lower limb undergrowth	Kyphoscoliosis	Lumbar scoliosis	Irregular vertebral endplates	Platyspondyly	Spondyloepimetaphyseal dysplasia
Disease(s) Associated with PAPSS2
spondyloepimetaphyseal dysplasia, Pakistani type

Mouse Phenotypes

decreased cranium height

malocclusion

domed cranium

arthritis

abnormal long bone epiphyseal plate morphology

abnormal long bone epiphyseal plate proliferative zone

abnormal long bone hypertrophic chondrocyte zone

decreased width of hypertrophic chondrocyte zone

decreased long bone epiphyseal plate size

decreased length of long bones

abnormal trabecular bone morphology

abnormal cartilage development

abnormal chondrocyte morphology

abnormal skeleton development

chondrodystrophy

abnormal bone ossification

abnormal endochondral bone ossification

abnormal chondrocyte physiology

Availability

Mouse Genotype

Papss2^bm/Papss2^bm

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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