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Symbol
Name
ID

Cxcr4
C-X-C motif chemokine receptor 4
MGI:109563

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Abnormal femoral metaphysis morphology	Abnormal tibial metaphysis morphology	Abnormal metaphysis morphology	Joint swelling	Pathologic fracture	Osteoporosis	Osteolysis	Osteosarcoma
Disease(s) Associated with CXCR4	Abnormal femoral metaphysis morphology	Abnormal tibial metaphysis morphology	Abnormal metaphysis morphology	Joint swelling	Pathologic fracture	Osteoporosis	Osteolysis	Osteosarcoma
osteoporosis
osteosarcoma

Mouse Phenotypes		decreased susceptibility to induced arthritis
Availability	Mouse Genotype	decreased susceptibility to induced arthritis
	Cxcr4^tm1Yiw/Cxcr4^tm1Yiw Tg(Lck-cre)1Jtak/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23